Ordered silicon nanocones arrays for label-free DNA quantitative analysis by surface-enhanced Raman spectroscopy

Ordered gold nanoparticle arrays as surface-enhanced Raman spectroscopy substrates for label-free detection of nitroexplosives.

Nitroexplosives, such as 2,4,6-trinitrotoluene (TNT) which is a leading example of nitroaromatic explosives, are causing wide concern. Motivated by the urgent demand for trace analysis of explosives, novel surface-enhanced Raman spectroscopy substrates based upon highly ordered Au nanoparticles have been fabricated by a simple droplet evaporation method. It is noteworthy that an ethylhexadecyld...

Quantitative label-free RNA detection using surface-enhanced Raman spectroscopy.

Surface-Enhanced Raman Spectroscopy (SERS) was performed to detect label-free RNA. We defined conditions which make it possible to probe the four bases of RNA, in single strands of polyadenosine (pA), polyuridine (pU), polycytosine (pC) and polyguanosine (pG). We therefore present below a quantitative analysis of mixtures of non-hybridized single strands, based on the deconvolution of the SERS ...

Label-Free Detection of Single-Base Mismatches in DNA by Surface-Enhanced Raman Spectroscopy**

Label free sub-picomole level DNA detection with Ag nanoparticle decorated Au nanotip arrays as surface enhanced Raman spectroscopy platform.

Label free optical sensing of adenine and thymine oligonucleotides has been achieved at the sub-picomole level using self assembled silver nanoparticles (AgNPs) decorated gold nanotip (AuNT) arrays. The platform consisting of the AuNTs not only aids in efficient bio-immobilization, but also packs AgNPs in a three dimensional high surface area workspace, assisting in surface enhanced Raman scatt...

Au nanorod arrays tailored for surface-enhanced Raman spectroscopy.

We have demonstrated surface-enhanced Raman spectroscopy (SERS) on arrays of Au nanorods aligned in line by a dynamic oblique deposition technique. For light polarized along the major axes of the nanorods, the plasma resonance of the Au nanorods has been tuned to a wavelength suitable for Raman spectroscopy. Raman scattering on the discrete nanorods is significantly enhanced compared with that ...